Throughout the economic life of a veterinary specialty, any modification, even if only minor (manufacturing site and procedure, improvement in the quality of the ingredients, side-effects observed, etc.), must be declared to the competent authorities. The technical monitoring of a veterinary medicine is constant, so as to ensure compliance with the regulations which themselves develop according to the new techniques introduced but also according to changes in behavior in civil society (for example, taking eco-toxicity into account in the use of a specialty). The regulatory status of a medicine is therefore not fixed.